Riboflavin

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China H&Z® Riboflavin Factory

Riboflavin/ Vitamin B2 CAS:83-88-5

Riboflavin/ Vitamin B2 Chemical Properties

MF:C17H20N4O6

MW:376.36

Melting point:290°C (dec.)(lit.)

Riboflavin/ Vitamin B2 Introduction:

Vitamin B2 (chemical formula: C17H20N4O6, formula 376.37), also known as riboflavin, is slightly soluble in water and stable when heated in neutral or acidic solutions. It is the component of the flavonoid auxiliary group in the body (the flavonoid plays the

role of hydrogen transfer in the biological REDOX). When it is lacking, it will affect the biological oxidation of the body and cause metabolic disorders. The lesions are mainly manifested as inflammation of the mouth, eyes and external genitalia, such as

keratitis, labitis, glossitis, eye conjunctivitis and scrotitis, etc., so this product can be used for the prevention and treatment of these diseases. The storage of vitamin B2 in the body is limited, so it should be provided daily by diet. Two properties of vitamin B2 are the main causes of its loss: (1) can be destroyed by light; (2) It can be destroyed by heating in

alkali solution.

Riboflavin/ Vitamin B2 Specification:

ITEM	SPECIFICATION	RESULT
Appearance	A yellow or orange yellow crystalline powder	Meets
Identification	Positive	Meets
Acidity or alkalinity	Check the color of the test solution after adding the respective solutions	Meets
Lumiflavin	Absorbance of the filtrate at 440nm does not exceed 0.025 (USP);	0.006
	not more than intense than BY6 (EP/BP)	Meets
Absorbance	0.31~0.33 A373nm/A267nm	0.32
	0.36~0.39 A444nm/A267nm	0.38
Particle size	100% passes through 80 mesh sieve	Meets
Specific rotation	Between -115°and -135°	-119°(USP)
	(BP/EP/USP)	-126°(BP/EP)
Loss on drying	≤1.5%	0.003
Heavy metals	<10ppm	Meets
Residue on ignition	≤0.3%(USP)	0.001
	≤0.1%(EP/BP)
Organic volatile impurities	Method IV <467>(USP)	Meets
Assay (on dry basis)	98.0-102.0%(USP)	99.0%(USP)
	97.0~103.0%(EP/BP)	100.0%(BP/EP)
Conclusion: The product complies with BP2008/EP5/USP32standard

 

Riboflavin/ Vitamin B2 Function:

The main physiological function of vitamin B2 is to promote metabolism as a coenzyme. H&Z® Riboflavin binds to phosphoric acid and a molecule of protein to form a flavin enzyme. These enzymes, also known as dehydrogenases, are important in mediating the transfer of hydrogen to the metabolism of sugars, fats, and amino acids. It is essential for the growth of many animals and microorganisms.

Vitamin B2 binds to specific proteins to form xanthase. Yellow enzyme plays a role in the transfer of hydrogen in the metabolism of substances and participates in the respiratory process of tissues.

 

Riboflavin/ Vitamin B2 Application

1.Riboflavin/ Vitamin B2 can accelerate the growth and regeneration of cells.

2.Riboflavin/ Vitamin B2 can accelerate the growth of the skin, nails, the hair.

3.Riboflavin/ Vitamin B2 helps eliminate the inflammation of the mouth, lips and tongue.

4.Riboflavin/ Vitamin B2 can enhance the eyesight and reduce fatigue of the eye.

5.Riboflavin/ Vitamin B2 interaction with other materials can help the metabolism of carbohydrates, fat and protein.