Phenacetin

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Product Description

China H&Z® Phenacetin is White, with shinning scaly crystals or white crystalline powder, odorless, slightly bitter taste. This product is dissolved in ethanol or chloroform, slightly dissolved in boiling water, very slightly dissolved in water

Product Detail

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China H&Z® Phenacetin Factory

Phenacetin CAS:62-44-2

Phenacetin Chemical Properties

MF:C10H13NO2

MW:179.22

Melting point :133-136°C(lit.)

Boiling point:132°C / 4mmHg

Density:1.1248 (rough estimate)

Phenacetin Specification:

Assay %≥99.0

organic chloride %≤0.02

p-Phenetidine≤light red、4#

Easy carbon compound≤4#、6#

Loss on drying%≤0.5

Melting point:134-137oC

Ignition residue %≤0.1

Phenacetin Introduction:

H&Z® Phenacetin is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXPhenacetin is a pain-relieving and fever-reducing drug,

Phenacetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.

This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Phenacetin has been linked to renal papillary necrosis in human beings [2, 3].

Phenacetin Application:

Antipyretic analgesic, used for the treatment of fever, headache, neuralgia, etc

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